Eduardo López-Collazo
ABOUT US
The immune response is activated in different clinical contexts that can be modeled in vitro. The first reaction of the Innate Immune System (IIS) is marked by an inflammatory response that is similar in different ways. However, the first steps produce a "deviation" towards an "alternative" response that can be carried out, in many cases, refractory states such as tolerance to endotoxins and tolerance to tumors. These refractory states may have researching values and their study is the objective of our research.
One of the major challenges of COVID-19 is the early identification of
those patients who will require deeper health care or will develope worse outcomes. After months of clinical testing and validation, we have been able to develop this calculator that classifies patients as low, intermediate and high risk upon arrival at the hospital. It does this based on only 4 parameters: age and three immune markers such as sCD86, sPD-L1 and sTim-3.
This will allow in an easy and simple way the triage of severe patients allowing a quicker treatment and follow-up.
